Silver Book Fact

Pre-surgery antibiotic use reduces 6-day mortality by 50% in elderly

Effective pre-surgery antibiotic use can reduce 60-day mortality in the elderly by 50%.

Silber J, Rosenbaum P, Trudeau M, Chen W, et al. Preoperative Antibiotics and Mortality in the Elderly. Ann Surg. 2005; 242(1): 107-14. http://journals.lww.com/annalsofsurgery/Abstract/2005/07000/Preoperative_Antibiotics_and_Mortality_in_the.15.aspx

Reference

Title
Preoperative Antibiotics and Mortality in the Elderly
Publication
Ann Surg
Publication Date
2005
Authors
Silber J, Rosenbaum P, Trudeau M, Chen W, et al
Volume & Issue
Volume 242, Issue 1
Pages
107-14
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Reduction of central-line infections saved ~ 1,800 lives and $280 million
    Standardization of best practice interventions reduced central line-associated blood stream infections and saved an estimated 1,800 lives and $280 million.  
  • Pre-surgery antibiotic use reduces 6-day mortality by 50% in elderly
    Effective pre-surgery antibiotic use can reduce 60-day mortality in the elderly by 50%.  
  • Over 8 years infection control practices saved ~27,000 lives and $1.8 billion
    Infection control practices saved an estimated 27,000 lives and $1.8 billion in medical costs between 2001 and 2009.  
  • Only a 20% reduction in drug-resistant infections would save $3.2 – $5.2 billion each year
    A 20% reduction in drug-resistant infections would save between 5.7 and 11.3 million additional hospital days and between $3.2 and $5.2 billion in healthcare costs, each year.  
  • An antibiotic stewardship program saved $17 million over 8 years
    An antibiotic stewardship program saved a total of $17 million over 8 years, with antibiotic costs rising $1 million in the first year after discontinuation.