Silver Book Fact

Brain imaging is showing that pain changes the structure and function of brain regions that perceive pain, making it persistent. These brain networks and receptor targets are being identified as potential targets for future therapies.

Apkarian V. The Brain in Chronic Pain: Clinical implications. Pain Manag. 2011; 1(6): 577-86. http://www.futuremedicine.com/doi/abs/10.2217/pmt.11.53

Reference

Title
The Brain in Chronic Pain: Clinical implications
Publication
Pain Manag
Publication Date
2011
Authors
Apkarian V
Volume & Issue
Volume 1, Issue 6
Pages
577-86
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • People with persistent pain who used complementary and alternative medicine (CAM) had lower average health care expenditures than nonusers ($3,797 versus $4,153).  
  • Researchers have developed several sub-types of ion channels that allow inflammation and growth factors to trigger persistent pain.  
  • 57% of American adults say they would pay an extra $1 per week in taxes in order to support government research into the causes of and treatment for chronic pain.  
  • Targeting A-type K+ channels in primary sensory neurons could provide a novel mechanism-based therapy for the treatment of bone cancer pain–one of the most severe types of chronic pain.  
  • Acupuncture, in combination with routine care, was associated with marked clinical improvements in patients with persistent low back pain. It has also shown improvement in primary and secondary outcomes…