Silver Book Fact

Brain imaging is showing that pain changes the structure and function of brain regions that perceive pain, making it persistent. These brain networks and receptor targets are being identified as potential targets for future therapies.

Apkarian V. The Brain in Chronic Pain: Clinical implications. Pain Manag. 2011; 1(6): 577-86. http://www.futuremedicine.com/doi/abs/10.2217/pmt.11.53

Reference

Title
The Brain in Chronic Pain: Clinical implications
Publication
Pain Manag
Publication Date
2011
Authors
Apkarian V
Volume & Issue
Volume 1, Issue 6
Pages
577-86
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Future Value

Related Facts

  • Researchers have discovered that some types of glial cells have a major impact on persistent neuropathic pain and that targeting these cells may result in a new class of disease…  
  • Topical clonidine gel significantly reduces foot pain in patients with painful diabetic neuropathy.  
  • Opioids have been found to reduce pain intensity and improve physical functioning for patients with persistent noncancer pain. It’s important to note that a decrease in mental health functioning…  
  • Use of stem cells to create neurons could enable the study of the response of human cells to new drugs in vitro, early in the drug development process.  
  • A meta-analysis of duloxetine, an anti-depressant, found a 50% reduction in pain at 12 weeks for diabetic peripheral neuropathy, and a 50% reduction in pain at 12 weeks for fibromyalgia.