Silver Book Fact

~One-third of shingles death preventable with vaccine

Approximately one-third of shingles deaths may be preventable through vaccination.

Mahamud, Abdirahman, Mona Marin, Steven P. Nickell, Trevor Shoemaker, John X. Zhang, et al. Herpes Zoster-Related Deaths in the United States: Validity of death certificates and mortality rates, 1979-2007. Clin Infect Dis. 2012; 55(7): 960-66. http://cid.oxfordjournals.org/content/55/7/960.full

Reference

Title
Herpes Zoster-Related Deaths in the United States: Validity of death certificates and mortality rates, 1979-2007
Publication
Clin Infect Dis
Publication Date
2012
Authors
Mahamud, Abdirahman, Mona Marin, Steven P. Nickell, Trevor Shoemaker, John X. Zhang, et al.
Volume & Issue
Volume 55, Issue 7
Pages
960-66
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value
  • Future Value

Related Facts

  • Use of shingles vaccines significantly reduced disease burden
    Use of a live attenuated VZV (varicella-zoster vaccine) in a randomized trial reduced the burden of illness from shingles by 61.1% and the incidence of postherpetic neuralgia (PHN) by 66.5%.  
  • Value of smallpox eradication
    An estimated $100 million spent in eradicating smallpox from 1967 to 1977 saved the world around $1.35 billion a year.  
  • Negative value of antibiotics to drug companies
    The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
  • Over 6 years, flu vaccine prevented ~13 million cases
    Over a 6-year period (2005 – 2011), the influenza vaccine prevented an estimated 13 million influenza cases–between 1.1 million and 5 million annually.  
  • Eradication of infectious diseases from vaccination
    Spanning more than 200 years of research and development, 10 infectious diseases have been at least 90 percent eradicated in the United States thanks to vaccines.