Silver Book Fact

An opiate agonist often used for persistent pain, tramadol was found in one meta-analysis to significantly reduce neuropathic pain when compared to placebo.

Duhmke R, Cornblath D, Hollingshead J. Tramadol for Neuropathic Pain. Cochrane Database of Neuropathic Pain. 2006; http://summaries.cochrane.org/CD003726/tramadol-for-neuropathic-pain

Reference

Title
Tramadol for Neuropathic Pain
Publication
Cochrane Database of Neuropathic Pain
Publication Date
2006
Authors
Duhmke R, Cornblath D, Hollingshead J
URL
Read Full Resource

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • The combination of information for neuroimaging and circulatory biomarkers could improve both the sensitivity and specificity of pain diagnosis and thereby improve treatment.  
  • Topical NSAIDs were found in a meta-analysis to be significantly more effective than placebo in reducing persistent pain from musculoskeletal conditions.  
  • People with persistent pain who used complementary and alternative medicine (CAM) had lower average health care expenditures than nonusers ($3,797 versus $4,153).  
  • An oral cannabinoid was found effective in relieving diabetic peripheral neuropathic pain symptoms and improving disturbed sleep, quality of life, and overall patient status.  
  • Use of stem cells to create neurons could enable the study of the response of human cells to new drugs in vitro, early in the drug development process.