Silver Book Fact

“Although high cholesterol was recognized as a key risk factor for cardiovascular disease in the 1970s, there were no good ways to reduce it. The best drug available was a grainy powder called cholestyramine. Patients mixed it with juice, but it tasted like sand–one patient said it was like drinking Miami Beach. Taking it was so unpleasant that it was prescribed for only the most severe cases.”

“Millions of people now control their cholesterol, and reduce their risk of heart disease, by swallowing a small pill just once a day. A new class of medicines, statins, was introduced in 1987 and offers a safe and effective way to lower cholesterol. One NIH official Claude Lenfant, even said that if all patients took statins according to guidelines, heart disease would no longer be the No. 1 killer.”

Categories

  • Innovative Medical Research
  • Human Value

Related Facts

  • Mortality rates in the first 3 months after a heart attack have fallen by about 75%.  
  • The use of ACE inhibitors in hypertensive patients 80 years of older was associated in this study with a 30% reduction in the rate of stroke and a 64% reduction…  
  • From 1970-2000, gains in longevity were greatest for people between the ages of 40 and 60, and greater for men than women, in large part because of advances in the…  
  • Effectiveness of treating ischemic strokert-PA within 3 hours of symptom onset
    A study of the  victims with effectiveness of treating ischemic strokert-PA within 3 hours of symptom onset showed a decrease in rehabilitation costs of $1.4 million and nursing home costs of…  
  • Satisfaction rates of heart valve disease patients with their treatment