Between 2010 and 2050, the total costs of caring for Americans with Alzheimer's disease--age 65 and older--will increase 5-fold--from $172 billion to $1.08 trillion each year.  These figures include the direct costs of care for all payers (Medicare, Medicaid, individuals with out-of-pocket costs, private insurance, HMOs, other managed care organzations, and uncompensated care).  They do not include the value of unpaid care provided by family and other caregivers--estimated at $144 billion in 2009.