Alendronate, a bisphosphonate, has been shown to reduce risk of hip fracture by around 53%, clinical vertebral fracture by 45%, and wrist fracture by 30%.
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Black, Dennis M. Desmond E. Thompson, Douglas C. Bauer, Kris Ensrud, Thomas Musliner, Marc C. Hochberg, Michael C. Nevitt, Shailaja Suryawanshi, and Steven R. Cummings; for the FIT Research Group. "Fracture Risk Reduction with Alendronate in Women with Osteoporosis: The fracture intervention trial". J Clin Endocrinol Metabo. Vol. 85, No. 11, pp. 4118-24. [ Permalink ] |