Stroke  /  Future Value

Stroke is the 5th leading cause of death in the U.S. and kills more than 129,000 people each year. Someone in the U.S. has a stroke about once every 40 seconds. People do survive stroke--around 795,000 strokes occur each year and there are an estimated 7 million stroke survivors in the U.S.--but they are often left with significant disabilities.

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    • Savings associated with t-PA treatment for ischemic stroke patients
      A $600 net savings is associated with each ischemic stroke patient treated with t-PA. In 2005, only 2% of all ischemic stroke patients received t-PA. If that percentage was increased…  
    • Stroke prevention through optimal anticoagulation
      If half of atrial fibrillation patients who currently receive warfarin in a routine care setting had their anti-coagulation optimized, around 9,000 strokes and more than 29,000 bleeds would be prevented.  
    • Cost-savings associated with optimal anticoagulation in AFib patients
      If half of all atrial fibrillation patients receiving suboptimal or no anticoagulation instead received optimal anticoagulation, 28,000 strokes could be prevented each year at a savings of around $2.5 billion in direct…  
    • There are 23 medicines in development for stroke, the third leading cause of death after heart disease and cancer.  
    • Following the current path, stroke cases will increase by 28.9% between 2003 and 2023 (estimates do not include strokes among the institutionalized population). If an alternative path is taken, there…  
    • According to the Pharmaceutical Research and Manufacturers of America, 13 medicines are currently in development for stroke.  
    • New approaches are under development to reduce ischemic stroke damage and other damage occuring because of stroke.  
    • The projected economic value of eliminating deaths from stroke is $7.6 trillion.  
    • Greater use of clot-busting drug t-PA in ischemic stroke patients could save the health care system over $100 million a year.  
    • Treating acute stroke with drugs that minimize cell death could result in a median decrease in disability of 30%. Treatment with stem cell transplants could result in a median decrease…  
    • Development of a neuroprotective drug could potentially reduce disability from stroke by 50%.  
    • Effectiveness of pacemaker/defibrillators to control AFib
      Widespread use of pacemaker/defibrillators to control atrial fibrillation could result in a 50% decrease in stroke.