Parkinson's Disease  /  Human Burden

Parkinson’s disease is a progressive neurological disorder that impacts close to one million Americans. It leads to debilitating symptoms, comorbidities, expensive medical care, and caregiving needs. Existing therapies help manage symptoms and exciting research advances hold promise for even better management and potential cures.

With educational support from Lundbeck, Roivant Sciences, and Sunovion.

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    • Premature Deaths Associated with Parkinson’s Disease
       
    • Parkinson’s Patients Who Experience Various Symptoms
       
    • Mortality Greater for Those With Parkinson’s Disease
       
    • Parkinson’s Disease Medicare Beneficiaries and Long-Term Care Facilities
       
    • Health Care Visits Due to Parkinson’s disease
       
    • Risk of Fracture from Parkinson’s Disease
       
    • Parkinson’s Disease Patients Who Report Falls
       
    • Symptoms of Parkinson’s Disease Psychosis in Half of Parkinson’s Disease Patients
       
    • Depression and Parkinson’s Disease Patients
       
    • Dementia is Nearly Inevitable for Parkinson’s Disease Patients
       
    • Experience of Americans With Parkinson’s Disease Over 1 Year
       
    • Close to half (48%) of all Parkinson’s patients report having suffered a fall.  
    • 26,000 hospice days in 2010 were attributable to Parkinson’s disease.  
    • 24,000 home health days in 2010 were attributable to Parkinson’s disease.  
    • 31,000 emergency department visits in 2010 were attributable to Parkinson’s disease.  
    • 57,000 outpatient visits in 2010 were attributable to Parkinson’s disease.  
    • 1.26 million physician office visits in 2010 were attributable to Parkinson’s disease.  
    • In 2010, Parkinson’s disease was the cause of 1.9 million hospital inpatient days–73% more than is expected for a population without the disease.  
    • Health-related-quality-of-life (HRQOL) is severely affected in Parkinson’s disease. In a study of veterans, HRQOL was more impaired in Parkinson’s disease than in those with any other condition.  
    • Among nursing home residents with Parkinson’s disease, 3-year mortality was 50%.  
    • Patients with Parkinson’s disease have twice the risk of suffering a fracture, and more than 3 times the risk of a hip fracture.  
    • Patients with Parkinson’s disease account for between 2.2% and 6.8% of the nursing home population in the U.S.  
    • Major depression is present in around 20-40% of Parkinson’s disease patients.  
    • More than 3/4 of Parkinson’s disease patients developed dementia during an 8-year study.  
    • Each year, around 68% of Parkinson’s disease patients suffer from falls.  
    • The risk of death in people with Parkinson’s disease is 1.6 times that of the general population.  
    • Some individuals with Parkinson’s disease talk, walk, or act out dreams and nightmares in their sleep. The may inadvertently injure themselves or their bed partners in the process.  
    • Lightheadedness, drooling, and difficulty swallowing can occur because of autonomic nervous system dysfunction in Parkinson’s disease.  
    • Many studies estimate that over 90% of Parkinson’s disease patients suffer from a type of sleep disturbance.  
    • At least 1/3 of patients with Parkinson’s disease develop cognitive impairment, which can be secondary to the disease itself.  
    • Psychiatric symptoms such as depression and anxiety occur in 1/3 to 2/3 of Parkinson’s disease patients.  
    • According to preliminary data, Parkinson’s disease was the 14th leading cause of death in the United States in 2004, causing 18,018 deaths.  
    • An estimated 33% of Parkinson’s patients suffer from falls; 13% fall more than once a week.  
    • As Parkinson’s progresses, substantial disability–including the inability to maintain balance, walk, speak, and move–makes assisted living and nursing home care necessary.  
    • By the time the symptoms of Parkinson’s disease are apparent, as much as 80% of dopamine-producing cells have been damaged.