Infectious Diseases  /  Economic Value

Vaccine preventable illnesses and diseases continue to cause significant sickness, hospitalization, pain, disability, and death in the United States.  Pneumonia causes somewhere between 300,000 and 600,000 hospitalizations in older adults each year, and more than 50% of flu-related hospitalizations are in people age 65 and older.  Around 50% of the more than 1 million cases of shingles each year are in people age 60 and older.

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    • Negative value of antibiotics to drug companies
      The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
    • Vaccines save lives and money
      Between 2001 and 2010, vaccine use prevented an estimated 170,000 severe pneumococcal infections and 10,000 deaths, and saved an estimated $310 million in direct medical costs each year.  
    • Significant savings from zoster vaccine
      In a cost-effectiveness analysis, investigators estimated the zoster vaccine cost $44,000 per quality-adjusted life year saved for a 70-year-old woman.  
    • Use of shingles vaccine could save $82 to $103 million
      Use of the shingles vaccine in immunocompetent adults ages 60 and older could save between $82 and $103 million in healthcare costs associated with the diagnosis and treatment of shingles,…  
    • Potential savings from shingles vaccine
      Use of the shingles vaccine in immunocompetent adults ages 60 and older could save between $82 and $103 million in healthcare costs associated with the diagnosis and treatment of shingles,…  
    • Economic value from flu vaccine in elderly
      As over 60% of the economic burden of influenza falls on those ages 65 and older, programs to reduce the impact of influenza on older Americans would have the greatest…  
    • Each flu case prevented could save $60 to $4,000
      The influenza vaccination could save between $60 and $4,000 per case prevented.  
    • Savings from flu vaccine
      Vaccination for influenza resulted in an average annual cost savings of $13.66 per healthy working adult vaccinated.  
    • Cost of pneumonia vaccine
      Addition of PCV13 (13-valent pneumococcal conjugate vaccine) to previously recommended pneumococcal polysaccharide vaccine for immunocompromised adults cost $70,937 per quality adjusted life year compared to no vaccine.  
    • Potential value of pneumonia vaccine
      Use of PCV13 (13-valent pneumococcal conjugate vaccine) in older adults is estimated to have the potential to reduce total healthcare costs by $3.5 billion and total societal costs by $7.4…  
    • Value of smallpox eradication
      An estimated $100 million spent in eradicating smallpox from 1967 to 1977 saved the world around $1.35 billion a year.  
    • Value of polio eradication
      Eradication of polio is estimated to produce savings to governments of $1.5 billion per year.  
    • Cost of measles much higher than vaccine
      One case of measles can cost 23 times as much as a single vaccination to prevent it.  
    • Cost effectiveness of MMR vaccine
      For every dollar spent on the MMR (measles, mumps, and rubella) vaccine, $21 is saved.  
    • Vaccines cost ~$50 per healthy life year saved
      Most vaccinations cost less than $50 per healthy life year saved. In contrast, treating hypertension costs between $4,340 and $87,940 per healthy life year saved.  
    • Cost savings from immunization
      Every dollar spent on immunization saves $6.30 in direct medical costs – a total savings of $10.5 billion. When including indirect costs such as lost days of work, disability,…  
    • Shingles vaccine would reduce healthcare use
      Use of the shingles vaccine in immunocompetent adults could eliminate more than 300,000 outpatient visits, 375,000 prescriptions, 9,700 emergency room visits, and 10,000 hospitalizations.  
    • Influenza vaccine use reduces antibiotic use
      Use of LAIV (live attenuated influenza virus) in healthy adults ages 18 to 65 reduced antibiotic use by 43% to 47%.  
    • Over 6 years, flu vaccine prevented >110,000 hospitalizations and 5.8 million medical visits
      Over a 6-year period (2005 – 2011), the influenza vaccine prevented more than 110,000 hospitalizations and 5.8 million medical visits.