Infection  /  Economic Value

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    • Negative value of antibiotics to drug companies
      The value of an antibiotic to a drug company is negative $50 million- compared to the positive value of $1 billion for a new musculoskeletal drug.  
    • Reduction of central-line infections saved ~ 1,800 lives and $280 million
      Standardization of best practice interventions reduced central line-associated blood stream infections and saved an estimated 1,800 lives and $280 million.  
    • Over 8 years infection control practices saved ~27,000 lives and $1.8 billion
      Infection control practices saved an estimated 27,000 lives and $1.8 billion in medical costs between 2001 and 2009.  
    • An antibiotic stewardship program saved $17 million over 8 years
      An antibiotic stewardship program saved a total of $17 million over 8 years, with antibiotic costs rising $1 million in the first year after discontinuation.  
    • Vaccines save lives and money
      Between 2001 and 2010, vaccine use prevented an estimated 170,000 severe pneumococcal infections and 10,000 deaths, and saved an estimated $310 million in direct medical costs each year.  
    • Only a 20% reduction in drug-resistant infections would save $3.2 – $5.2 billion each year
      A 20% reduction in drug-resistant infections would save between 5.7 and 11.3 million additional hospital days and between $3.2 and $5.2 billion in healthcare costs, each year.  
    • Significant savings from zoster vaccine
      In a cost-effectiveness analysis, investigators estimated the zoster vaccine cost $44,000 per quality-adjusted life year saved for a 70-year-old woman.  
    • Use of shingles vaccine could save $82 to $103 million
      Use of the shingles vaccine in immunocompetent adults ages 60 and older could save between $82 and $103 million in healthcare costs associated with the diagnosis and treatment of shingles,…  
    • Potential savings from shingles vaccine
      Use of the shingles vaccine in immunocompetent adults ages 60 and older could save between $82 and $103 million in healthcare costs associated with the diagnosis and treatment of shingles,…  
    • Potential cost effectiveness of shingles vaccines
      The projected cost-effectiveness of a shingles vaccine for adults age 60 and older was estimated at $15,390 – $22,474 from the payer perspective, and $14,450 to $21,524 from the societal…  
    • Cost-effectiveness of flu vaccine
      Vaccination for pandemic influenza (pH1N1) prior to an outbreak produces incremental cost-effectiveness ratios for individuals without high risk conditions, ranging from $8,000 to $52,000 per quality-adjusted life year.  
    • Economic value from flu vaccine in elderly
      As over 60% of the economic burden of influenza falls on those ages 65 and older, programs to reduce the impact of influenza on older Americans would have the greatest…  
    • Each flu case prevented could save $60 to $4,000
      The influenza vaccination could save between $60 and $4,000 per case prevented.  
    • Savings from flu vaccine
      Vaccination for influenza resulted in an average annual cost savings of $13.66 per healthy working adult vaccinated.  
    • Cost of pneumonia vaccine
      Addition of PCV13 (13-valent pneumococcal conjugate vaccine) to previously recommended pneumococcal polysaccharide vaccine for immunocompromised adults cost $70,937 per quality adjusted life year compared to no vaccine.  
    • Potential value of pneumonia vaccine
      Use of PCV13 (13-valent pneumococcal conjugate vaccine) in older adults is estimated to have the potential to reduce total healthcare costs by $3.5 billion and total societal costs by $7.4…  
    • Value of smallpox eradication
      An estimated $100 million spent in eradicating smallpox from 1967 to 1977 saved the world around $1.35 billion a year.  
    • Value of polio eradication
      Eradication of polio is estimated to produce savings to governments of $1.5 billion per year.  
    • Cost of measles much higher than vaccine
      One case of measles can cost 23 times as much as a single vaccination to prevent it.  
    • Cost effectiveness of MMR vaccine
      For every dollar spent on the MMR (measles, mumps, and rubella) vaccine, $21 is saved.  
    • Vaccines cost ~$50 per healthy life year saved
      Most vaccinations cost less than $50 per healthy life year saved. In contrast, treating hypertension costs between $4,340 and $87,940 per healthy life year saved.  
    • Cost savings from immunization
      Every dollar spent on immunization saves $6.30 in direct medical costs – a total savings of $10.5 billion. When including indirect costs such as lost days of work, disability,…  
    • Shingles vaccine would reduce healthcare use
      Use of the shingles vaccine in immunocompetent adults could eliminate more than 300,000 outpatient visits, 375,000 prescriptions, 9,700 emergency room visits, and 10,000 hospitalizations.  
    • Influenza vaccine use reduces antibiotic use
      Use of LAIV (live attenuated influenza virus) in healthy adults ages 18 to 65 reduced antibiotic use by 43% to 47%.  
    • Over 6 years, flu vaccine prevented >110,000 hospitalizations and 5.8 million medical visits
      Over a 6-year period (2005 – 2011), the influenza vaccine prevented more than 110,000 hospitalizations and 5.8 million medical visits.