Every day, 10,000 Americans celebrate their 65th birthday. While the U.S. is experiencing a longevity revolution, at the same time our aging nation is triggering a Silver Tsunami of chronic age-related disease that bring with it increased national health care spending, high rates of morbidity and mortality, and declines in quality of life.
In 2015, more than 1.6 million new cases of cancer are expected to be diagnosed and close to 600,000 people will die from the disease. Thankfully, major breakthroughs are changing how we prevent, treat, and cure cancer. Treatments are becoming increasingly personalized and advances in immuno-oncology, a field that uses the body’s own immune system to fight cancer, are causing a paradigm shift in cancer treatment. Use the navigation below and the search feature to view the data and to narrow down your search. This volume of The Silver Book produced with educational support from Pfizer.
Approximately 82 million Americans suffer from some form of cardiovascular disease (CVD) and close to 1 in 3 deaths result from CVD. These are not only deadly but costly diseases with CVD and stroke costing around $300 billion each year.
Every year around 75,000 Americans learn that they have atrial fibrillation (AFib)—the most common type of arrhythmia, or abnormal heart rhythm. Having AFib puts people at an increased risk for stroke, which can be both deadly and costly. Medicare alone is estimated to pay billion per year to treat newly diagnosed atrial fibrillation patients. This volume of The Silver Book was produced with educational support from Daiichi-Sankyo.
Stroke is the 4th leading cause of death in the U.S. and kills more than 133,000 people each year. People do survive stroke–around 795,000 strokes occur each year and there are an estimated 7 million stroke survivors in the U.S.–but they are often left with significant disabilities.
Each year around 75,000 Americans are diagnosed with atrial fibrillation (AF), 900,000 experience a venous thromboembolism event (VTE), and 800,000 have a stroke. The burden for those who survive is enormous and the cost of care a major expense for individuals and the nation. Fortunately research advances are offering significant hope. A number of investigative anticoagulants have the potential to reduce strokes in AF patients while also reducing the risk of bleeds; clot-dissolving agents are proving to lessen the effects of strokes; and the same drugs in the pipeline for AF could prevent VTE after major orthopedic surgery. This volume of The Silver Book was produced with educational support from Daiichi-Sankyo.
While medical innovations and public health gains in the past century have been measurable in leaps and bounds, significant progress against acute disease has revealed an equally enormous challenge—chronic disease on an unprecedented scale. Close to half of Americans have chronic conditions and 1 in 4 have more than one. They cause 7 out of every 10 deaths and cost our country 75 cents of every health care dollar. With chronic disease prevalence growing at a faster rate than the population as a whole, the forecast is daunting.
Despite recent advances, diabetes continues to be a major health threat for at least 25 million Americans and growing. The biggest concerns for individuals with the disease are its many complications and co-morbidities; which can cause vision loss, heart disease, stroke, and other debilitating medical conditions. With the aging of the population and the rise in risk factors like obesity, these problems are going to skyrocket, making medical innovation more critical than ever. This volume of The Silver Book produced with educational support from Roche.
Every year, between 50,000 and 90,000 adults in the U.S. die from vaccine-preventable infectious diseases or their complications. Many serious infectious diseases are acquired in the healthcare setting and those healthcare-associated infections cost U.S. hospitals between $28.4 and $45 billion each year.
Healthcare-associated infections (HAIs) are acquired while receiving medical or surgical care for other conditions in hospitals, physician offices, long-term care facilities, and other healthcare settings. They are largely preventable, yet often costly and deadly, and rapidly becoming a national crisis as they increasingly develop resistance to drugs. This volume of The Silver Book produced with educational support from Cubist Pharmaceuticals.
Vaccine preventable illnesses and diseases continue to cause significant sickness, hospitalization, pain, disability, and death in the United States. Pneumonia causes somewhere between 300,000 and 600,000 hospitalizations in older adults each year, and more than 50% of flu-related hospitalizations are in people age 65 and older. Around 50% of the more than 1 million cases of shingles each year are in people age 60 and older. This volume of The Silver Book produced with educational support from Pfizer.
Between 5 and 10 million Americans acquire pneumonia, 35 to 50 million are afflicted with influenza, and 1 million get herpes zoster (shingles)–each year. Older Americans are much more likely to get these infections and to suffer from complications and death. In fact, the death rate from pneumonia and influenza combined is close to 130 times higher in people age 85 and older, compared to people ages 45 to 54. Thankfully, vaccinations are available for many of the most common and deadly infectious disease in older Americans, and can save countless lives and healthcare dollars. This volume of The Silver Book produced with educational support from Pfizer.
The prevalence of diseases like Alzheimer’s and Parkinson’s are skyrocketing as our population ages and they threaten to bankrupt our economy if better treatments and cures aren’t found. This volume of The Silver Book produced with educational support from Novartis
As many as 5.1 million Americans are living with Alzheimer’s disease–the sixth-leading cause of death. This disease threatens to bankrupt our economy as our nation ages. Produced with educational support from Novartis.
As many as 1 million Americans live with Parkinson’s disease. This disease is costly and devastating, often leading to disability and death. Produced with educational support from
More than 44 million Americans face the threat of osteoporosis; which causes more than 2 million fractures each year. These fractures can have a profound impact on quality of life—often leading to pain, disability, loss of independence, and even death—and cost the U.S. an estimated billion each year. Fortunately, scientists are continuing to make exciting breakthroughs that are helping to keep bones healthy and prevent debilitating fractures. The Alliance for Aging Research partnered with the National Osteoporosis Foundation to produce this volume. Educational support came from Novartis.
Around 100 million Americans live with persistent pain–more Americans than are affected by diabetes, heart disease, and cancer combined. This volume of The Silver Book produced with educational support from
More than 38 million Americans age 40 and older are blind, visually impaired, or have an age-related eye disease, and adult vision loss costs our economy more than billion a year. With major advances in vision research bringing new prevention and treatments, it is critical that support for research and incentives for innovation remain a priority. The Alliance for Aging Research has teamed up with the Alliance for Eye and Vision Research (AEVR) during their Decade of Vision, to release Volume II of The Silver Book®:Vision Loss. Volume II brings updated data on vision loss in older Americans, as well as the exciting changes and discoveries in vision research and treatment. This volume of The Silver Book® was produced in partnership with NAEVR and with educational support from Bausch & Lomb.
Vaccine-preventable diseases or their complications account for 50,000 to 90,000 adult deaths in the U.S. each year.
Approximately 1.7 million Americans develop hospital-acquired HAIs each year.
Atrial fibrillation is the most common heart arrhythmia in the U.S. Often going undiagnosed, AFib prevalence estimates vary between 2.7 million and 6.1 million Americans.
At age 60, 1 in 25 Americans have AFib. At age 80+, this increases to nearly 1 in 10.
As our population continues to age, prevalence of Afib is going to skyrocket, to a projected 5.6 to 15.9 million adults by 2050.
Projected increases in the prevalence of Afib
AFib is a major economic burden for the U.S. with at least $6.65 billion in healthcare costs attributable to the disease each year. This estimate may be low. One study estimates that Medicare alone pays $15.7 billion per year to treat newly diagnosed AFib patients.
The risk of having a stroke increases 5-fold in individuals with AFib. Individuals with AFib also have more severe and recurrent strokes than those without the disease.
Distribution of inpatient and selected outpatient costs for treating AFib.
Stroke is very disabling and individuals recovering from a stroke who also have AFib have a higher risk of remaining disable or handicapped compared to stroke patients without AFib.
AFib can also lead to heart failure. Within the first year of diagnosis, AFib patients have a 36.7% chance of experiencing heart failure– compared to 10.4% in those without AFib.
Individuals with AFib have a twice the risk of dementia.
Alliance for Aging Research launches new version of The Silver Book® site that offers a modern design, intuitive navigation, and a content-rich experience. With an emphasis on visualization of data, such…